WebFeb 1, 2016 · To investigate the function of HDAC activity during inner ear development, zebrafish embryos were continuously treated from 12 hours post fertilization (hpf) onwards with 0.1 μM TSA or 100 μM VPA. WebOct 1, 2024 · Zebrafish models are widely utilized in studying inner ear development due to its rapid external embryonic development and optical clarity for observing the embryos (Whitfield et al., 2002; Wei et al., 2008). The inner ear structure of zebrafish is presented in Supplemental Fig. 1. In zebrafish, the precursors originate from the common pro ...
Zebrafish Inner Ear Development and Function Request PDF
WebJan 29, 1996 · The zebrafish provides an important model for vertebrate inner ear development. The otic placode becomes visible at approximately 16 hours (at 28.5 degrees C) and forms a vesicle with a lumen by cavitation at approximately 18 hours. Two otoliths appear in the lumen by 19.5 hours, and at about 24 hours the first sensory hair cells are … WebThis dissertation focuses on the development and regulation of both sensory and neuronal cell populations. The sensory epithelium is established by the basic helixloop- helix transcription factor Atoh1. Misexpression of atoh1a in zebrafish results in induction of ectopic sensory epithelia albeit in limited regions of the inner ear. city of bryan animal shelter
Atlas of the developing inner ear in zebrafish - Bever - 2002 ...
WebIn addition, for more information on the topics of development and regeneration, the reader is referred to recent reviews on the morphogenesis of the zebrafish inner ear and development of the sensory epithelia (Alsina and Whitfield, 2016), or hair-cell regeneration in the lateral line organ (Kniss et al., 2016). WebFeb 20, 2024 · This study indicated that toluene may affect the development of both the inner ear and lateral line systems in zebrafish, while the lateral line system may be more sensitive to toluene than the inner ear. ... Toluene altered the expression level of genes involved in ear development/function in zebrafish, among which the mRNA levels of … Web2 days ago · Retinoic acid signaling has also been implicated in zebrafish ear development, specifically regulating the development of the semicircular canals and otoliths. Disruption of this pathway results in a circling behavior previously associated with inner ear malformations (Mackowetzky et al., 2024). donate a wig for cancer patients