Hif1 gpi
WebHIF-1 が誘 導する遺伝子は、血管新生、赤血球産生、アポトーシス制御、細胞増殖、解糖系亢進、 pH 調節、薬剤抵抗など多岐にわたり機能を調節している。 しかし、HIF-1 … Web3 de set. de 2024 · Hypoxia-inducible factor 1 (HIF1) is a transcription factor that exerts pivotal regulatory role in oxygen homeostasis by controlling both the delivery and utilization of oxygen [Citation 6]. HIF1α is the functional subunit of HIF1 and important to the HIF1 activation under hypoxia condition [ Citation 7 ].
Hif1 gpi
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WebAlthough HIF1-alpha and platelet derived growth factor-B (PDGF-B) are expressed in glioma tissue and closely related to tumor angiogenesis mediating vascular endothelial growth factor (VEGF) activity, their direct relationship has not yet been clarified. The aim of this study is to investigate whether HIF1-alpha regulates PDGF-B expression. Web9 de dez. de 2024 · These HIF1A downstream targets include genes associated with general hypoxic response (e.g., CA9, TGM2), glycolysis (e.g., GPI, PGK1), and …
WebHIF（Hypoxia Inducible Factor; 低酸素誘導因子）は、細胞内が低酸素状態に陥った際に活性化される転写因子であり、HIF-1α と HIF-1β からなるヘテロ二量体です。. この転写 … WebHIF（Hypoxia Inducible Factor; 低酸素誘導因子）は、細胞内が低酸素状態に陥った際に活性化される転写因子であり、HIF-1α と HIF-1β からなるヘテロ二量体です。 この転写因子は低酸素状態へ順応するため、VEGF、EPO（エリスロポエチン）、グルコース・トランスポーター、各種糖分解酵素など各種タンパク質の転写を促進します。 HIF-1α 抗体一覧 …
Web27 de dez. de 2024 · Here, we set out to identify the direct HIF1 and HIF2 targets at the chromatin level in the human hematopoietic system by performing genome-wide ChIP … WebImmunogen: Human HIF-1α aa. 610-727 Application: Western blot (Routinely Tested), Immunofluorescence (Tested During Development) Target Molecular Weight: 120 kDa Concentration: 250 µg/ml RRID: AB_398272 Storage Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. Regulatory Status: RUO View All …
Web27 de jun. de 2011 · These include the transporters Glut1 and MCT4 and glycolytic enzymes HK2 (hexokinase 2), GPI (glucose-6-phosphate isomerase), TPI (triosephosphate …
WebStructure. HIF1 is a heterodimeric basic helix-loop-helix structure that is composed of HIF1A, the alpha subunit (this protein), and the aryl hydrocarbon receptor nuclear translocator (), the beta subunit.HIF1A contains a basic helix-loop-helix domain near the C-terminal, followed by two distinct PAS (PER-ARNT-SIM) domains, and a PAC (PAS … small angled screwdriverWeb1 de ago. de 2004 · The ability to sense and respond to changes in oxygenation represents a fundamental property of all metazoan cells. The discovery of the transcription factor … small angle hypertropiaWeb2 de ago. de 2010 · HIF1 antibody (Novus Biologicals) was used to pull down HIF1 protein. Immunoprecipitated samples were run on 7.5% SDS-PAGE and X-ray films were exposed to the dried gel for 6 wk. HIF1 -activity assay. APE-1 shRNA cells were transfected with the respective expression plasmids, with a combination of small angled wire shelvesWebFull gene name according to HGNC. Hypoxia inducible factor 1 subunit alpha. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to … small angle grain boundariesWeb11 de fev. de 2016 · No significant correlation between HIF-1 α /EP300 expression and myeloma cell proliferation or GPI was identified ( Supplementary Figures S2A and B ). … solid wood seagull acoustic guitarWebSummary of HIF1A (bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8) expression in human tissue. Mainly nuclear expression with cases of cytoplasmic expression. Including … small angle measurementWebVisualization of AMF/GPI and AMFR/gp78 function. (1) Intracellularly, AMF works as glucose-6-phosphate isomerase (GPI), contributing to glycolysis and gluconeogenesis. … small angled water sprayer for a garden hose