Hipk2 domains
Webb6 sep. 2015 · 1 Department of Pathology, University of California San Francisco, San Francisco, CA 941432 Department Physiology, University of California San Francisco, Sa ... ,干细胞之家 - 中国干细胞行业门户第一站 WebbInterleukin-21 (IL-21) is a pleiotropic cytokine that regulates T-cell, B-cell, NK-cell, and myeloid-cell functions. IL-21 binds with its cognate receptor complex, which consists of the IL-21 receptor (IL-21R) and the common gamma chain.We identified a novel IL-21R-binding molecule, WSB-1, which contains WD-40 repeats and a SOCS-box domain.
Hipk2 domains
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Webbeffects of HIPK2 on p53-dependent gene expression, suggesting that Axin stimulates HIPK2 by physically occupying an autoinhibitory domain of HIPK2.26 HIPK2 … Webb1 mars 2024 · HIPK2 contains an N-terminal kinase domain, a SUMO (small ubiquitin-related modifier) attachment site , a protein-protein interaction region, a homeobox …
WebbMCE 引用文献:PMID: 36004621 Introduction: The present study aimed to investigate the effect of homeodomain interacting protein kinase 2 (HIPK2) on pulmonary fibrosis and the probable mechanisms. Material and methods: We constructed a mouse model of bleomycin-induced pulmonary fibrosis and up-regulated the expression of HIPK2 in the … Webb21 mars 2024 · HIPK4 (Homeodomain Interacting Protein Kinase 4) is a Protein Coding gene. Diseases associated with HIPK4 include Adenosquamous Lung Carcinoma.Gene Ontology (GO) annotations related to this gene include transferase activity, transferring …
WebbThe kinase is regulated by both sumoylation (8) and ubiquitination (9,10). Ubiquitination and subsequent degradation of HIPK2 is inhibited by DNA damaging agents. Caspase … Webb8 jan. 2024 · HIPK2 Cooperates with KRAS Signaling and Associates with Colorectal Cancer Progression. Exercise and cardioprotection: A ""HIP"" side of HIPK2 in the …
WebbHomeodomain-interacting protein kinases (HIPK1, HIPK2, HIPK3) can interact with the homeobox transcription factors Nkx-1.2. 63 HIPK3 acts as a novel positive regulator of pdx-1 abundance through phosphorylation of pdx-1 (positive regulator of insulin biosynthesis). 64 It is also a direct target of miR-187 with down-regulated expression levels in …
WebbQuery Target Key Target Name Description P-Value MaxTC; compound_1 . Q6L709_HHV2: TK: Thymidine kinase: 3.343e-85: 0.36: KITH_HHV1S form 1116 exceptionWebbThyroid cancer incidences have been steadily increasing worldwide and are projected to become the fourth leading cancer diagnosis by 2030. Improved diagnosis and … form 1116 copy 1 foreign tax credit comp wksWebbHomeodomain-interacting protein kinase 2 (HIPK2) is a serine-threonine kinase that acts as a transcriptional regulator and corepressor for homeodomain transcription factors … form 1116 examples filled inWebb21 mars 2024 · HIPK2 is a target for SENP1 desumoylation regulated by the cytoplasmic-nuclear shuttling of SENP1. HIPK2 neutralizes MDM2 inhibition … difference between pepsi max and diet pepsiWebbView()/(6-Fluoro-1H-indazol-3-ol) information and documentation regarding (6-氟-1H-吲唑-3-醇), including NMR, HPLC, LC-MS, UPLC & more. form 1116 explanationWebbDescription: Mus musculus transformation related protein 73 (Trp73), transcript variant 3, mRNA. (from RefSeq NM_001126331) RefSeq Summary (NM_001126331): This gene encodes tumor protein p73, which is a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include … form 1116 instructions 2022 pdfWebb1 sep. 2024 · In order to investigate the function of HIPK2 for chromatin compaction, HIPK2 was fused to the DNA-binding domains of Gal4 or LacI, thus allowing its … difference between pepsi and pepsico