WebR175H p53 expression was rescued by addition of proteasome inhibitor MG132 to CB002, suggesting a role for ubiquitin-mediated degradation of the mutant protein. In summary, CB002, a p53 pathway-restoring compound that targets mutant p53 for degradation and induces tumor cell death through NOXA, may be further developed as a cancer therapeutic. WebRXF393-027WCY Optional Service: Optional requirements on this protein: Product Overview : RXF393 (Human Kidney Renal Cell Carcinoma) Whole Cell Lysate: Description : XF393 cell …
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WebStauprimide is a staurosporine analog that promotes embryonic stem cell (ESC) differentiation. Stauprimide is a non-broad spectrum inhibitor that binds to the MYC transcription factor NME2 and blocks its nuclear localization in ESCs, which results in down-regulation of MYC transcription. - Mechanism of Action & Protocol. http://ezbiosystems.com/view2.asp?d_id=321 i know the girl
Kidney Cancer Xenograft - Altogen Labs
WebXenograft nonclinical studies can be conducted to find more complex treatment for patients with advanced stage disease. The DU-145 epithelial cell line was isolated from prostate carcinoma cells of a 69-year-old Caucasian male. DU … WebNSC59984 is a p53 pathway activator via induction of mutant p53 protein degradation and p73 activation. NSC59984 specifically restores p53 pathway signaling and induces p73-dependent cell death in mutant p53-expressing human colorectal cancer cells. NSC59984 also induces cell death in a panel of cancer cell lines bearing different p53 mutations ... WebRXF393 (Human Kidney Renal Cell Carcinoma) Whole Cell Lysate. Product Code. LY500043. Skip to the end of the images gallery. Skip to the beginning of the images gallery. $235.00. … i know the feeling images